Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

1;Front Cover;1 2;Annual Reports in Medicinal Chemistry, Volume 23;4 3;Copyright Page;5 4;CONTENTS;6 5;CONTRIBUTORS;12 6;PREFACE;14 7;SECTION I: CNS AGENTS;16 7.1;Chapter 1. Antipsychotic Agents;16 7.2;Chapter 2. Analgesics;26 7.3;Chapter 3. Antianxiety Agents and Anticonvulsants;34 7.4;Chapter 4. Agents for the Treatment of Cognitive Disorders;44 7.5;Chapter 5. Central Nervous System Actions of Adenosine Agonists and Antagonists;54 7.6;Chapter 6. Central Serotonin Receptors: Opportunities for Drug Discovery;64 8;SECTION II: CARDIOPULMONARY AND VASCULAR AGENTS ;74 8.1;Chapter 7. Antihypertensive Agents;74 8.2;Chapter 8. Pulmonary and Antiallergy Agents;84 8.3;Chapter 9. Peripheral Actions of Selective Muscarinic Agonists and Antagonists;96 8.4;Chapter 10. Vasopressin Antagonists;106 8.5;Chapter 11. Atrial Natriuretic Peptide;116 8.6;Chapter 12. Plasminogen Activators;126 9;SECTION III: CHEMOTHERAPEUTIC AGENTS ;136 9.1;Chapter 13. Beta-Lactam Antibiotics;136 9.2;Chapter 14. Quinolone Antibacterial Agents;148 9.3;Chapter 15. Novel Approaches Toward Discovery of Antibacterial Agents;156 9.4;Chapter 16. Chemical Modification of Antibodies for Cancer Chemotherapy;166 9.5;Chapter 17. Antiviral Agents;176 10;SECTION IV: ENDOCRINOLOGY, IMMUNOLOGY AND METABOLIC DISORDERS ;186 10.1;Chapter 18. Immunomodulatory Approaches to the Treatment of Inflammation;186 10.2;Chapter 19. Modulation of Arachidonic Acid Metabolism in the Treatment of Rheumatoid Arthritis ;196 10.3;Chapter 20. The Pharmacological Treatment of Obesity;206 10.4;Chapter 21. Gastrointestinal Motility Enhancing Agents;216 10.5;Chapter 22. Luteinizing Hormone Releasing Hormone Analogs In Control of Fertility and Gonadal Hormone Dependent Disease;226 11;SECTION V: TOPICS IN BIOLOGY ;236 11.1;Chapter 23. Structure and Function of G-Protein Coupled Receptors;236 11.2;Chapter 24. G-proteins as Receptor-Effector Couplers;250 11.3;Chapter 25. Isozymes of Protein Kinase C;258 11.4;Chapter 26. Therapeutic Strategies in the
Treatment of AIDS;268 11.5;Chapter 27. Enzyme Changes Linked to Anticancer Drug Resistance;280 12;SECTION VI: TOPICS IN CHEMISTRY AND DRUG DESIGN ;290 12.1;Chapter 28. Applications of NMR Spectroscopy to Protein Structure Determination;290 12.2;Chapter 29. Search Strategies for Determining Bioactive Conformers of Peptides and Small Molecules;300 12.3;Chapter 30. Oligonucleotide Inhibitors of Gene Expression in Living Cells: New Opportunities in Drug Design;310 12.4;Chapter 31. Enzyme Assisted Transformations in Organic Media;320 12.5;Chapter 32. Mechanistic Aspects of Xenobiotic Metabolism as Related to Drug Design;330 13;SECTION VII: SPECIAL TOPICS ;340 13.1;Chapter 33. To Market, To Market 1987;340 14;COMPOUND NAME, CODE NUMBER AND SUBJECT INDEX;364 15;CUMULATIVE CHAPTER TITLES KEYWORD INDEX, VOLUMES 123 ;374 16;CUMULATIVE CONTRIBUTOR INDEX, VOLUMES 123;382 17;CUMULATIVE NCE INTRODUCTION INDEX, 19831987;394 18;CUMULATIVE NCE INTRODUCTION INDEX, 19831987, BY INDICATION;400