Science writer Bijal P. Trivedi gives a comprehensive look at cystic fibrosis, from its late 1930s discovery to the recent development of breakthrough treatments for 90% of patients, and the way treatments for the previously fatal disease are opening the door for curing other life-threatening conditions.
Inhaltsverzeichnis
Contents
Introduction
Part IChapter 1: Hello, Joey 1974Chapter 2: The Treatment Plan 1974Chapter 3: Case 44: Babies Hospital, New York City 1935Chapter 4: A New Disease 1936-1937Chapter 5: An Equal Opportunity Disease 1938-1942Chapter 6: Christmas Homecoming 1974-1977Chapter 7: The Sweat Test 1943-1960Chapter 8: A Tribe of Desperate Parents 1950-1955Chapter 9: Lessons from Polio 1955-1960Chapter 10: The Registry 1960-1966Chapter 11: The Therapist 1977Chapter 12: A Disease in Search of Ideas 1964-1980Chapter 13: The Hitman Cometh 1979-1982Chapter 14: Salt and Water 1970-1981Chapter 15: Salty Boy 1981-1983Chapter 16: Birth of an Advocate 1984 Chapter 17: Out of Many, One 1978-1984
Part 2Chapter 18: The Gene Hunters 1980-1984Chapter 19: Lucky Number Seven 1984-1985Chapter 20: Kate 1986Chapter 21: To Screen or Not to Screen Newborns 1985Chapter 22: Michigan 1985Chapter 23: Joey's Long Goodbye 1986Chapter 24: Mad Pursuit 1987Chapter 25: The Gene 1989Chapter 26: Runny, Like Water 1989-1994Chapter 27: Venture Philanthropy-A New Way to Fund Drug Development 1977-1999Chapter 28: The Gene Is the Medicine 1989-1991Chapter 29: Transforming the Lungs 1992-2003Chapter 30: First-in-Human Trials 1992-1993Chapter 31: The Beall Curve 1996
Part 3Chapter 32: The Joey Fund 1989-1999Chapter 33: A Network for Developing Therapeutic Drugs 1997-1998Chapter 34: Aurora 1998-1999Chapter 35: The Gates Open 1987-2000Chapter 36: A Tale of Four Families-CF in the New Millennium 1999Chapter 37: The Takeover 2001Chapter 38: Getting the Band Together 2001-2003Chapter 39: Pay to Play 2002-2004Chapter 40: Molecular Architects of Vertex West 2004-2005Chapter 41: Rat to Man 2003-2004Chapter 42: A Christmas Gift 2004-2005Chapter 43: The Lucky Four 2005-2007Chapter 44: The Doorman Launches the Era of Genetic Medicine 2007-2008Chapter 45: Disruption Fall 2008Chapter 46: Tasting like Average People 2010-2012Chapter 47: Milestones to a Cure 2004-2015Chapter 48: Tackling the Common Mutation 2004-2013Chapter 49: What Mutation Are You? 2013-2014Chapter 50: The Mother of All Deals 2014Chapter 51: Very Personal Clinical Trials 2021-2017Chapter 52: The Triple 2015-2017Chapter 53: The Home Stretch 2018Chapter 54: The Leftovers 2015-2020Chapter 55: A New Generation 2017-2020
Epilogue 2019-2020
AcknowledgmentsTimelineEndnotesAbout the Author
