A one-stop, comprehensive, and thoroughly updated resource for students, professors, and researchers alike
Thoroughly revised and updated, the Third Edition of Supramolecular Chemistry delivers a comprehensive and integrated approach to this rapidly evolving and quickly expanding field. Distinguished professors and authors Jonathan Steed and Jerry Atwood provide readers with a broad and exhaustive resource that assumes little in the way of prior knowledge of supramolecular chemistry.
Extensive new content on cutting edge research throughout the field including molecular machines and the mechanical bond, mechanochemistry, halogen bonding, and crystal nucleation accompanies full-color imagery and study problems designed to help students understand and apply the principles introduced within the book. Additional material is provided in the supplementary online resources, including solutions to the student exercises and PowerPoint slides of the figures in the book. Supramolecular Chemistry, Third Edition also includes:
* The latest research and developments reported over the last decade
* A unique "key references" system that highlights crucial reviews and primary literature
* A description of key experimental techniques included in accessible "boxes" for the non-expert
* Exercises and problems for students, complete with online solutions
* Full-color illustrations and imagery designed to facilitate learning and retention of the key concepts and state-of-the art of the field
Perfect for undergraduate and postgraduate students taking courses on supramolecular chemistry, the Third Edition of Supramolecular Chemistry also belongs on the bookshelves of all researchers in this, and any closely related, fields. Academics, in particular postdoctoral students and professors, will benefit significantly from this text.
Inhaltsverzeichnis
About the Authors xvii
Preface to the Third Edition xix
Acknowledgements xxi
About the Front Cover xxiii
About the Companion Website xxiii
Chapter 1 Concepts 1
1. 1 Definition and Development of Supramolecular Chemistry 1
1. 2 Classification of Supermolecule Formation 4
1. 3 Receptors, Coordination, and the Lock and Key Analogy 11
1. 4 Binding Constants 14
1. 5 Cooperativity, Multivalency, and the Chelate Effect 29
1. 6 Preorganisation and Complementarity 36
1. 7 Thermodynamic and Kinetic Selectivity, and Discrimination 38
1. 8 Nature of Supramolecular Interactions 40
1. 9 Solvation Effects 57
1. 10 Supramolecular Concepts and Design 61
1. 11 Practical Applications of Supramolecular Chemistry 73
Chapter 2 The Supramolecular Chemistry of Life 83
2. 1 Biological Inspiration for Supramolecular Chemistry 83
2. 2 Alkali Metal Cations in Biochemistry 84
2. 3 Porphyrins and Tetrapyrrole Macrocycles 96
2. 4 Supramolecular Features of Plant Photosynthesis 99
2. 5 Uptake and Transport of Oxygen by Haemoglobin 106
2. 6 Enzymes and Coenzymes 111
2. 7 Signalling: Neurotransmitters, Hormones, and Pheromones 117
2. 8 DNA and the Genetic Code 121
2. 9 Biochemical Self-Assembly 134
2. 10 Biomineralisation 137
2. 11 Emergence of Life 141
Chapter 3 Cation-Binding Hosts 147
3. 1 Introduction to Coordination Chemistry 147
3. 2 Podands 153
3. 3 The Crown and Lariat Ethers 158
3. 4 The Cryptands 163
3. 5 The Spherands 165
3. 6 Nomenclature of Cation-Binding Macrocycles 167
3. 7 Selectivity of Cation Complexation 169
3. 8 Solution Behaviour and Applications of Crowns and Cryptands 184
3. 9 Macrocycle Synthesis: The Template Effect and High Dilution 189
3. 10 Soft Ligands for Soft Metal Ions 196
3. 11 Proton Binding: The Simplest Cation 212
3. 12 Complexation of Organic Cations 217
3. 13 Alkalides and Electrides 231
3. 14 The Calixarenes 234
3. 15 Carbon Donor and pi-acid Ligands 244
3. 16 The Siderophores 250
Chapter 4 Anion Binding 265
4. 1 Introduction 265
4. 2 Biological Anion Receptors 268
4. 3 Concepts in Anion Host Design 274
4. 4 Cationic Receptors 283
4. 5 Neutral Receptors 300
4. 6 Boron Based Receptors and Lewis Acid Chelates 319
4. 7 Metal-Containing Receptors 323
4. 8 Anion-Binding Helices 333
4. 9 Anion Transport 336
Chapter 5 Ion-Pair Receptors 351
5. 1 Simultaneous Anion and Cation Binding 351
5. 2 Labile Coordination Complexes and Cages as Anion Hosts 367
5. 3 Receptors for Zwitterions 375
Chapter 6 Molecular Guests in Solution 381
6. 1 Molecular Hosts and Molecular Guests 381
6. 2 Intrinsic Curvature: Guest Binding by Cavitands 384
6. 3 Cyclodextrins 401
6. 4 Molecular Tweezers, Clips and Clefts 411
6. 5 Cyclophane Hosts 415
6. 6 Constructing a Solution Host from Clathrate-Forming Building Blocks: The Cryptophanes 440
6. 7 Covalent Cages: Carcerands and Hemicarcerands 450
6. 8 Coordination Cages 460
6. 9 Halogen-Bonded Complexes 461
Chapter 7 Solid-State Inclusion Compounds 469
7. 1 Nomenclature and Thermochemical Aspects 469
7. 2 Porosity and Gas Sorption 473
7. 3 Clathrate Hydrates 479
7. 4 Urea and Thiourea Clathrates 486
7. 5 Channel Cl
