This book examines in detail the role of innovative radiation techniques in the management of prostate cancer, including IMRT, IGRT, BART, and modern brachytherap. It also explores a range of current controversies in patient treatment.
Today, the arsenal of "high-precision" or "targeted" radiotherapy includes a variety of techniques and approaches that, like the pieces of a puzzle, need to be put together to provide the prostate cancer patient with high-level optimized radiation treatment. This book examines in detail the role of these innovative radiation techniques in the management of prostate cancer. In addition, a variety of current controversies regarding treatment are carefully explored, including whether prophylactic treatment of the pelvic lymphatics is essential, the magnitude of the effect of dose escalation, whether a benefit accrues from hypofractionation, and what evidence exists for the superiority of protons or heavy ions. Radiotherapy in Prostate Cancer: Innovative Techniques and Current Controversies is intended for both radiation oncologists and urologists with an interest in the up-to-date capabilities of modern radiation oncology for the treatment of prostate cancer.
Inhaltsverzeichnis
Imaging, delineation and immobilization: MRI and MR-spectroscopy. - PET imaging in prostate cancer. - Phase contrast X-ray imaging- next generation CT imaging. - Organ contouring for IMRT. - General aspects of patient immobilization. - Internal immobilization: From rectal balloon to hyaluronic acid. - Clinical endpoints: Biochemical recurrence a valuable endpoint? . - Overall and disease-free survival too long to wait? . - Late toxicity current scoring concepts. - Quality of life: Assessment and Correlates. - Dose escalation and new radiation techniques: Dose escalation an update on randomized clinical trials. - IMRT for prostate cancer. - IGRT- how and when. - Tracking in prostate cancer. - Locally advanced disease: Techniques of pelvic lymphatic irradiation. - Prophylactic treatment of the pelvic lymphatics: pro. - Prophylactic treatment of the pelvic lymphatics: contra. - Hormonal therapy and radiation therapy - randomized and prospective trials. - Treatment of clinically involved lymph nodes. - Hypofractionation: Hypofractionation in prostate cancer- biological aspects. - Hypofractionation: Clinical data. - Simultaneous integrated boost techniques. - Brachytherapy: Principals of 3D, highly conformal brachytherapy. - Seed implantation. - HDR brachytherapy. - Adjuvant treatment and salvage treatment: Target volume definition in postoperative radiotherapy. - Randomized trials for adjuvant radiotherapy. - Salvage radiotherapy after radical prostatectomy. - Salvage prostatectomy after radiotherapy. - Use of protons and heavy ions: Proton therapy for prostate cancer: technological and clinical aspects. - There is evidence for the superiority of protons or heavy ions, pro. - There is evidence for the superiority of protons or heavy ions, contra.
