This book is a comprehensive study of the subject of ionic
interactions in macromolecules. The first parts of the book review
and analyze the conventional treatments of fixed charges (e. g. in
polyelectrolytes and polyampholytes), including screening and
condensation by mobile ions. The interaction of ions with less
polar sites on the macromolecule (e. g. amide bonds), and the origin
of the lyotropic effects (focusing on binding versus condensation)
will also be extensively addressed.
The book also explores complex micellar organizations involving
charged macromolecules (e. g. DNA) and low-molecular-weight
ampholytes and strong protein associations. The resulting
structures are relevant to a variety of functional biological
systems and synthetic analogs. The contribution of electrostatic
and hydrophobic interaction to the stability of proteins and other
supramolecular structures will also be analyzed. There are chapters
on applications such as deionization and cosmetic formulation.
This 21-chapter book is divided into three sections:
* Fundamentals
* Mixed Interactions
* Functions and Applications