Inhaltsverzeichnis
#A Investigative Approaches to Organelle Disturbances. - #A-1 Investigation of ischaemic effects on subcellular structures by centrifugation methods. - #A-2 Investigation of subcellular derangements in human biopsy material. - #A-3 Analytical subcellular studies in alcoholic liver disease. - #A-4 Methodological approaches in studies of altered mitochondrial and peroxisomal ? -oxidation. - #A-5 Pharmacological and toxicological aspects of peroxisome proliferators. - #A-6 Studies on the mechanisms of changes produced in the liver, thyroid, pancreas and kidney by hypolipidaemic drugs and di-(2-ethylhexyl) phthalate. - #A-7 The use of cytochrome P-450 isoenzymes as an index of endoplasmic reticulum changes. - #A-8 Drug-induced mitochondrial proliferation. - #A-9 Ultrastructural morphometric/biochemical approaches to assessing metal-induced cell injury. - #A-10 Iron overload, lysosomes and free radicals. - #A 11 Glucocerebrosidase, a membrane-associated lysosomal enzyme deficient in Gaucher disease. - #A 12 Cytochemical techniques applied to whole tissue and tissue homogenates. - #NC(A) Supplementary Items. - #NC(A)-1 Immunoelectron microscopical localization of lysosomal hydrolases in normal and I-cell fibroblasts. - #B Approaches Depending on Surface Distinctions. - #B-1 Free-flow electrophoresis: its application to the separation of cells and cell membranes. - #B-2 Counter-current chromatography as a tool in subcellular studies. - #B-3 Flow cytometry: a tool in studying cellular derangements. - #B-4 Interaction of Paf-acether with the human platelet: receptor binding and pharmacology. - #NC(B) Supplementary Items. - #NC(B) Supplementary Items. - #C Plasma Membrane and Cytoskeleton. - #C-1 Membrane-mediated cytotoxicity: measurement of changes and their prevention by divalent cations. - #C-2Complement-mediated plasma-membrane damage: effects on cell physiology, prospects of cell recovery and implications for disease mechanisms. - #C-3 Erythrocyte membrane derangements associated with sickle cell disease. - #C-4 The membrane-cytoskeletal axis in phagocytosing PMN- leucocytes and virally transformed fibroblasts. - #NC(C) Supplementary Items. - #NC(C)-1 Studies on cell injury: effects of ion regulation on cell membranes and the cytoskeleton. - #NC(C)-2 The glycoproteins and fluidity of multinodular goiter euthyroid plasma membranes. - #D Epithelial Membranes in Digestive Tissues. - #D-1 Gastroduodenal epithelial cells: the role of the apical membrane in mucosal protection. - #D-2 Structural and functional aspects of the intestinal brush border. - #D-3 Studies of the mechanisms of mucosal iron uptake. - #D-4 Pancreatic acinar cell plasma-membrane enzymes involved in stimulus-secretion coupling. - #NC(D) Supplementary Items. - #NC(D) Supplementary Items. - #E Studies Focused on Endocytosis, Proteases or Invasiveness. - #E-1 Receptor-mediated uptake of a toxin which binds to plasma-membrane ion channels. - #E-2 Lysosomal proteolysis in cultured hepatocytes. - #E-3 Hepatic processing of insulin: characterization and modulation. - #E-4 Receptor-mediated endocytosis in rat liver parenchymal and non-parenchyma1 cells, studied by means of subcellular fractionation in density gradients. - #E-5 Use of chromogenic peptide substrates in the study of proteolytic enzymes and mechanisms regulating them. - #E-6 Peptidases in connective tissue degradation and remodelling in reproductive and invasive tissues. - #E-7 Brain tumour cell invasion: possible role of lysosomal enzymes. - #E-8 Investigation of tumour-invasion mechanisms. - #NC(E) Supplementary Items. - #NC(E)-1 Plasma membrane distributionof metalloproteinases and cysteine proteinases in metastatic human cancer cells. - #NC(E)-2 Proteases and oxidants in injury to alveolar epithelial cells caused by lung-derived neutrophils in vitro. - #NC(E)-3 Autophagy and protein degradation in rat hepatocytes, studied by means of subcellular fractionation in Nycodenz gradients. - #NC(E)-4 Immunochemical techniques in the study of protein degradation with particular reference to collagen. - #F Renal Investigations. - #F-1 A nuclear magnetic resonance approach to investigate the biochemical and molecular effects of nephrotoxins. - #F-2 Enzyme release in nephrotoxicity and renal disease. - #F-3 The investigation of subcellular derangements in nephrotoxicity. - #F-4 Heterogeneity and function of kidney cortex lysosomes. - #F-5 Involvement of kidney lysosomes in the nephrotoxicity of cadmium and other metals. - #F-6 Lysosomal populations in kidney cortex of rats with heavy proteinuria. - #F-7 Immune derangements in experimental, toxin-induced autoimmune nephropathies. - #F-8 Glomerular basement membrane and the inflammatory response. - #F-9 Biochemical and immunological characterization of basement membranes in renal disease. - #Nc(F) Supplementary Items. - #Nc(F) Supplementary Items. - with Sub-index.
