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Inhaltsverzeichnis
Opening Remarks. - Chemistry and Physiology of Lipoproteins. - The Interaction of Apolipoprotein-Alanine (ApoC-III) with Lipids: Study of Structural Features Required for Binding. - Lipoproteins and Lipid Transport. - Pathways of Lipoprotein Metabolism: Integration of Structure, Function and Metabolism. - Steroid Requirements for Suppression of HMG-CoA Reductase Activity in Cultured Human Fibroblasts. - The Immunology of Serum Lipoproteins. - Biochemical Pharmacology of Hypolipidemic Drugs. - Hormone-Induced Lipolysis and the Metabolic Pathways Providing Energy to the Cell: A Possible Role of ATP as a Rate-Limiting Factor. - Mechanism of Action of Hypolipidemic Drugs. - Newer Hypolipidemic Compounds. - Experimental and Clinical Evaluation of Two Atromid-S Analogues in Relation to Their Differential Modes of Action. - Approaches to Treatment of Hyperlipidemias. - Pathogenesis of Hyperlipidemias, Clues to Treatment? . - Serum Lipoprotein Composition in Different Types of Hyperlipoproteinemia. - Diet in the Management of Hyperlipidemic Patients. - The Partial Ileal Bypass Operation in Treatment of the Hyperlipidemias. - Drugs and Thrombosis. - The Activation and Inhibition of Fibrinolysis. - The Role of Lipids in the Tissue Factor Pathway of Blood Coagulation. - Use of Fibrinopeptide A Measurements in the Diagnosis and Management of Thrombosis. - Modifications of Platelet Functions by Dietary Fats. - Risk Factors Other than Diet. - Diabetes as a Risk Factor for Arteriosclerotic Vascular Disease. - Hypertension and Other Risk Factors. - The Heritable Hyperlipoproteinemias and Atherosclerosis. - Smoking and Carbon Monoxide Uptake as a Risk Factor in Atherosclerotic Cardiovascular Disease. - Risk of Coronary Disease and Coronary Complications by Neural and Psychological Factors. - Animal Models forAtherosclerosis Research. - New Animal Model for Atherosclerosis Research. - Effects of Various Hypolipidemic Drugs on Fatty Acid Composition of Liver and Serum Lipids. - Some Aspects of the Chimpanzee as a Model for Experimental Atherosclerosis. - Studies on Experimental Atherosclerosis by Immunofluorescence. - The Effects of Tolbutamide on the Development of Atherosclerosis in Rhesus Monkeys Fed an Average American Table-Prepared Diet. - The Cockerel as an Animal Model for Atherosclerosis Research. - Influence of Platelets on the Integrity of the Vessel Wall. - Scope and Organization of a Lipid Clinic and Clinical Trials. - Scope and Organization of a Lipid Clinic and Clinical Trials. - Portacaval Shunt in Two Patients with Homozygous Hypercholesterolemia. - Planning the Type II Coronary Primary Prevention Trial of the Lipid Research Clinics (U. S. A.). - Concluding Remarks. - Abstracts of Submitted Papers. - Author Index.
