The Molecular Basis of Autism

Name: The Molecular Basis of Autism
Brand: Springer
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This book is a comprehensive overview of the clinical and scientific aspects of Autism from the leading experts in the field. The clinical section covers everything from epidemiological features to epigenetic regulation to behavioral therapies and much in between. The basic science section presents the latest knowledge on the underlying causes of the disorder including the role of various neurotransmitters, neurexins and neuroligins, reelin, and other proteins. Chapters also explore the cognition and motor control in autism and the connection between oxidative stress and mitochondrial dysfunction and autism. The thorough description of these underlying causes may help researchers and clinicians find more effective treatments and therapies for the 1 in 68 American children who have been diagnosed with Autism.

Inhaltsverzeichnis

Preface. - A Brief History of Autism. - Autism Spectrum Disorder: Diagnostic Considerations. - Epidemiologic Features of Autism Spectrum Disorders. - Genetics of Autism Spectrum Disorders: The Opportunity and Challenge in the Genetics Clinic. - Epigenetic Regulation in Autism. - Immunology of Autism. - Neuroimaging in Autism Spectrum Disorders. - The Neuropathology of Autism. - Pharmacology of ASD Spectrum Disorder. - Behavioral Therapies. - Autism and Dopamine. - Autism and Glutamate. - Serotonin in Autism Spectrum Disorder: Insights From Human Studies and Animal Models. - Oxytocin and Vasopressin in Autism and Genetic Syndromes. - Molecular basis of cholinergic changes in autistic spectrum disorders and relevance for treatment interventions. - Reelin, GABA, FMRP, and Autism. - The Role of Neurexins and Neuroligins in Autism. - Neurotrophins, their receptors and autism: ligand vs. receptor abnormalities. - Cognition, Motor Control and Other Aspects of Autism: A Pragmatic Review. - Increased vulnerability to oxidative stress and mitochondrial dysfunction in autism. - Index.

Produktdetails

Erscheinungsdatum

05. Oktober 2016

Sprache

englisch

Seitenanzahl

456

Reihe

Contemporary Clinical Neuroscience

Herausgegeben von

S. Hossein Fatemi

Verlag/Hersteller

Springer

Produktart

kartoniert

Abbildungen

XVIII, 437 p. 38 illus., 17 illus. in color.

Gewicht

686 g

Größe (L/B/H)

235/155/25 mm

Sonstiges

Previously published in hardcover

ISBN

9781493954711

Herstelleradresse

Springer Nature Customer Service Center GmbH, Europaplatz 3, 69115 Heidelberg, ProductSafety@springernature.com

Entdecken Sie mehr

Neurowissenschaften

Entwicklungspsychologie

Psychiatrie

Neurowissenschaften

Entwicklungspsychologie

Psychiatrie

Pressestimmen

This is a timely overview of the rapidly evolving
findings in the neurobiology of autism spectrum disorder (ASD). This
collection will be useful to clinicians in psychiatry, neurology, behavioral
sciences, pharmacology, and clinical genetics, as well as scientists across
disciplines studying neurodevelopmental disorders. It is indeed a valuable
addition to the libraries of clinicians and scientists working in the field of
neurodevelopmental disorders. (Latha V. Soorya, Doody s Book Reviews, January,
2016)

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Produktdetails