Molecular Basis and Emerging Strategies for Anti-aging Interventions

This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction that will be of interest to scientists and researchersfrom various disciplines in the life sciences.

Chapter 1.
Hormesis and Hormetic drugs for healthy ageing and longevity. -
Chapter
2.
Intermittent fasting dietary restriction as a geroprotector. -
Chapter
3.
Anti-aging properties of Mediterranean diet components in human. -
Chapter
4.
Activation of plasma membrane redox system: A novel anti-aging strategy. -
Chapter
5.
Beneficial effects of alternate-day fasting and calorie restriction on the risk factors for age related diseases. -
Chapter
6.
Role of phytochemicals in eliciting longevity genes. -
Chapter
7.
Autophagy induction: A promising anti-aging strategy. -
Chapter
8
. The potential role of stem cell reprogramming in anti-aging. -
Chapter
9
. Anti-aging strategies based on telomerase activity. -
Chapter
10.
Epigenetic modification is an attractive target for therapeutic anti-aging intervention. -
Chapter
11
. Antioxidants for health and longevity. -
Chapter
12
. Current approaches of anti-inflammatory dependent anti-aging strategies. -
Chapter
13.
Anti-aging therapeutics based on rapalogs and mTOR inhibitors Exercise-induced anti-aging mechanisms. -
Chapter
14
. AMPK activation: An emerging anti-aging strategy. -
Chapter
15.
Sirtuin activators and brain aging. -
Chapter
16.
Glycolytic inhibitors as tools for developing caloric restriction mimetics.
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Chapter
17.
Novel classification perspective of geroprotective and senolytic drugs as an anti-aging strategy. -
Chapter
18
. The place of geroprotective agents in life quality and longevity of companion animals. -
Chapter
19
. Management of sarcopenia for successful aging. -
Chapter
20
. Impact of sarcopenia and sarcopenic obesity in healthy aging. -
Chapter
21
. Klotho levels may be an innovative approach for mitigating age-related diseases. -
Chapter
22
. Melatonin and its anti-aging activity.