Biochemistry, Cell and Molecular Biology, and Genetics

Integrates biochemical, molecular, and cellular health and disease processes into one essential text!

Biochemistry, Cell and Molecular Biology, and Genetics: An Integrated Textbook by Zeynep Gromley and Adam Gromley is the first to cover molecular biology, cell biology, biochemistry (metabolism), and genetics in one comprehensive yet concise resource. Throughout the book, these topics are linked to other basic medical sciences, such as pharmacology, physiology, pathology, immunology, microbiology, and histology, for a truly integrated approach.

Key Highlights

• Easy-to-read text enhances understanding of underlying molecular mechanisms of disease
• Nearly 500 illustrations and tables help reinforce chapter learning objectives
• Textboxes throughout make connections with other preclinical disciplines
• End of unit high-order clinical vignette questions with succinct explanations help integrate basic science topics with clinical medicine

This textbook provides a robust review for medical students preparing for courses as well as exams. Dental, pharmacy, physician's assistant, nursing, and graduate students in pre-professional/bridge programs will also find this a beneficial learning tool.

This book includes complimentary access to a digital copy on https://medone. thieme. com.

Part I
1. Anatomy of the Cell and Organelles
2. DNA Replication, Gene Mutations, and Repair
3. Transcription and Regulation of Transcription
4. Translation and Regulation of Translation
Part II
5. Cytoskeleton
6. Protein Sorting, Modifications, and Intracellular Traffic
7. Membrane Transport
8. Extracellular Matrix
9. Cell Adhesion and Membrane Junctions
10. Signal Transduction
11. Cell Cycle and Control of the Cell Cycle
12. Stem Cells and Hematopoiesis
13. Cell Injury, Apoptosis, and Necrosis
14. Hallmarks of Cancer and Cancer Biology
15. Molecular Principles of Cancer Treatments and Therapies
Part III
16. Enzymes and Enzyme Kinetics
17. Regulation of Enzyme Activity
18. Structure and Function of Proteins
19. Molecular and Biological Techniques
20. Plasma Proteins and the Diagnostic Use of Enzymes
Part IV
21. Digestion and Absorption of Carbohydrates
22. Glycolysis
23. Metabolism of Fructose, Galactose and the Pentose Phosphate Pathway (HMP Shunt)
24. Glycogen Metabolism and Regulation
25. Gluconeogenesis
26. Pyruvate Dehydrogenase and Tricarboxylic Acid (TCA) Cycle
27. Electron Transport Chain (ETC) and Oxidative Phosphorylation
28. Oxygen Toxicity and Antioxidants
29. Oxidation of Fatty Acids and Ketogenesis
30. Acid Base Chemistry and Acid Base Disorders
31. Glucose Homeostasis and Maintenance of Blood Glucose Concentrations
Part V
32. Digestion and Absorption of Proteins
33. Nitrogen Metabolism
34. Amino Acid Metabolism
35. Amino Acid Derivatives
36. Porphyrin Heme Metabolism and Iron Homeostasis
37. Nucleotide Metabolism
38. Vitamins in One-Carbon Metabolism
Part VI
39. Digestion and Absorption of Lipids
40. Synthesis of Fatty Acids and Triacylglycerols
41. Metabolism of Membrane Lipids and Lipid Derivatives
42. Cholesterol Metabolism
43. Blood Lipoproteins
44. Steroid Hormones and Vitamin D
45. Nutrition and Metabolism
46. Vitamins and Minerals
Part VII
47. DNA Packaging and Meiosis
48. Cytogenetics: Chromosomal Basis of Human Diseases
49. Single Gene Disorders: Autosomal Dominant and Recessive Inheritance
50. Sex-Linked and Non-Traditional Modes of Inheritance
51. Population Genetics
52. Genomic Imprinting and Epigenetics
53. Gene Interactions and Multifactorial Inheritance
54. Personalized Medicine
55. Developmental Genetics
56. Cancer Genetics