Circadian Rhythms, Sleep and Inflammation

The circadian clock is a complex cellular mechanism that controls numerous key physiological processes and maintains cellular, tissue, and systemic homeostasis. Disruption of the clock system influences the immune response and brain functions. Immune activation is closely linked with inflammation, neurodegeneration, aging, and other peripheral and central nervous system-related abnormalities. There is increasing evidence that cellular inflammation affects sleep and circadian rhythms and vice-versa. This book offers a structured overview that focuses on the multi-angle interaction of circadian rhythms, sleep, and inflammatory response in normal or pathological conditions.

Circadian Regulation of Neuroinflammation. - Circadian Regulation of Peripheral Inflammation. - Sleep and Neuroinflammation. - Sleep and Circadian Rhythm in Peripheral Inflammation: Realm of Interconnected Frontiers. - Neuro-Inflammatory Response and Immune-Brain Crosstalk in Sleep Regulation. - Sleep and Circadian Disruption in Depression and Anxiety Disorders: An Inflammatory Insight. - Inflammatory Impact on Sleep, Shizophrenia, and Autism Spectrum Disorder. - Chronobiological Aspects of Aging, Neurodegeneration, and Inflammation. - Sleep, Aging, and Inflammation: Unravelling the Connections.