Nanotechnology Empowered Vaccine Delivery

This book offers a comprehensive exploration of advanced vaccine delivery systems, emphasizing how nanotechnology can enhance immunogenicity and overall vaccine performance. It provides an in-depth examination of vaccine categories, mechanisms of action, and the development of innovative nanocarriers, including nanogels, polymeric nanoparticles, and transdermal platforms. Dedicated chapters discuss the application of nanotechnology in addressing diseases such as cancer, asthma, HIV, and COVID-19, alongside essential considerations related to safety, toxicity, pharmacokinetics, and regulatory frameworks. With contributions from leading experts, the book delivers valuable insights for researchers and professionals working to advance next-generation vaccine design and delivery technologies.

1. History of vaccines. - 2. Vaccine administration: Route and site. - 3. Types of Vaccines: From Traditional to Cutting-Edge Technologies. - 4. Immunological mechanism of vaccination. - 5. Development and mechanism of adjuvants-based vaccines. - 6. Nanomaterials in the Vaccine Development. - 7. Nanotechnology-mediated transdermal delivery of vaccines. - 8. Nanogels-mediated delivery of vaccines. - 9. Polymeric-based nanoparticles-mediated delivery of vaccines. - 10. Advances in nanotechnology in mRNA vaccines. - 11. Nanotechnology-mediated delivery of vaccines in the cancer management. - 12. Nanotechnology-mediated delivery of vaccines in asthma management. - 13. Nanotechnology-mediated delivery of vaccines in HIV prevention. - 14. Nanotechnology-mediated delivery of vaccines in COVID-19 management. - 15. Myths and facts associated with the vaccine development: challenges, safety and efficacy. - 16. Preclinical and clinical development of vaccines. - 17. Regulatory aspects and considerations of vaccines in clinical trials.