Animal Models in Cardiovascular Research

This fully revised and updated third edition reflects intensified interest in the field and provides information essential to researchers interested in using animal models for cardiovascular research, or any research requiring normal cardiovascular function.

General Principles of Animal Selection and Normal Physiological Values. - Preanesthesia, Anesthesia, Chemical Restraint, and the Recognition and Treatment of Pain and Distress. - Normal Cardiac Function Parameters. - Measuring Cardiac Function. - Measuring Vascular Function and Ventricular/Arterial Coupling Dynamics. - Isolated Heart Preparations, Problems, and Pitfalls. - Cardiovascular Effects of Anesthetics, Sedatives, Postoperative Analgesic Agents, and Other Pharmaceuticals. - Naturally Occurring and Iatrogenic Animal Models of Valvular, Infectious, and Arrhythmic Cardiovascular Disease. - Iatrogenic Models of Ischemic Heart Disease. - Iatrogenic, Transgenic, and Naturally Occurring Models of Cardiomyopathy and Heart Failure. - Iatrogenic, Congenic, and Transgenic Models of Hypertension. - Naturally Occurring, Iatrogenic and Transgenic Models of Atherosclerotic Disease. - Animal Models for the Study of Neurohumeral and Central Neural Control of the Cardiovascular System. - Other Transgenic Animal Models Used in Cardiovascular Studies.