Cutaneous adverse drug reactions are common and range from the benign to those which are life-threatening. The clinical presentation of these dermatoses is varied and many may mimic common skin conditions. Consequently, diagnosis in drug-induced skin disease is challenging and the treatment considerations are complex. This book aims to bridge the divide between dermatology and allergy by providing a comprehensive review on the pathomechanisms and clinical features of cutaneous adverse drug reactions. Broken up into three distinct sections: General Considerations, Reaction Patterns, and Special Drug Categories, these chapters cover the common and rare adverse skin reactions and provide information on recent advances - particularly immunopathology and pharmacogenetics - as well as highlighting new adverse drug signals and novel therapies. Drug Eruptions is a must-have resource for dermatologists, allergists, internal physicians and general practitioners.
Inhaltsverzeichnis
Section I: General Considerations
. - Chapter 1: Pharmacogenetics of Cutaneous Adverse Drug Reactions. - Chapter 2: Mechanisms of Drug Hypersensitivity. - Chapter 3: Histopathology of Cutaneous Adverse Drug Reactions. - Chapter 4: Skin Tests in Evaluating Drug Eruptions. - Chapter 5: In vitro Drug Allergy Testing. -
Section II: Reaction Patterns
. - Chapter 6: Drug-induced urticaria. - Chapter 7: Exanthematous Drug Eruptions. - Chapter 8: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. - Chapter 9: Acute Generalized Exanthematous Pustulosis. - Chapter 10: Drug Reaction Eosinophilia and Systemic Symptoms (DRESS). - Chapter 11: Fixed Drug Eruptions and Generalized Bullous Fixed Drug Eruptions. - Chapter 12: Lichenoid Drug Eruptions. - Chapter 13: Drug-induced Connective Tissue Disorders. - Chapter 14: Drug-induced Vasculitis. - Chapter 15: Drug-induced Autoimmune Bullous Diseases. - Chapter 16: Other Drug-induced Inflammatory Skin Reactions. - Chapter 14: Drug-induced Vasculitis. - Chapter 15: Drug-induced Autoimmune Bullous Diseases. - Chapter 16: Other Drug-induced Inflammatory Skin Reactions. - Chapter 17: Drug-induced Photosensitivity. - Chapter 18: Drug-induced Pruritus Without Primary Rash. - Chapter 19: Drug-induced Nail Changes. - Chapter 20: Drug-induced Hair Changes. - Chapter 21: Drug-induced Pigmentary Disorders. -
Section III: Special Drug Categories
. - Chapter 22: Immediate and Delayed Reactions to Beta-lactams. - Chapter 23: Hypersensitivity Reactions to Iodinated Radiocontrast Media. - Chapter 24: Cutaneous Adverse Reactions to Biologic Agents. - Chapter 25: Cutaneous Reactions to Oncologic Targeted Therapy. - Chapter 26 :Cutaneous Reactions to Oncologic Immunotherapy.
